Bone and Joint Infections: From Microbiology to Diagnostics by W. Zimmerli

By W. Zimmerli

Bone and Joint Infections is the 1st booklet to take a multidisciplinary method of masking the motives and therapy of osteomyelitis and septic arthritis. right and quick prognosis of bone and joint an infection calls for the enter of various experts, and Bone and Joint Infection takes a similarly collaborative and comprehensive approach, together with chapters from a diverse crew of clinicians, researchers, and surgeons.

Covering either the elemental microbiology and medical features of bone and joint an infection, this booklet could be a helpful source either for researchers within the lab and for physicians and surgeons looking a accomplished reference on osteomyelitis and septic arthritis.

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Extra info for Bone and Joint Infections: From Microbiology to Diagnostics and Treatment

Example text

Gram staining of the fluid may be helpful but is diagnostic in only 50% of cases [53]. Blood Cultures Blood cultures must be collected before beginning antimicrobial agents to optimize the possibility of isolating the pathogen(s); an exception is the septic patient, in whom delayed antibiotic therapy is associated with patient mortality. In such cases, an attempt to obtain 2 Microbiology of Bone and Joint Infections 17 blood cultures may be made, but it should not delay initiation of antibiotic therapy.

38] Berbari E, Mabry T, Tsaras G, et al. Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg 2010;92(11):2102–2109. [39] Bottner F, Wegner A, Winkelmann W, et al. Interleukin-6, procalcitonin and TNF-alpha: markers of peri-prosthetic infection following total joint replacement. J Bone Joint Surg Br 2007;89(1):94–99. [40] Trampuz A, Hanssen AD, Osmon DR, et al. Synovial fluid leukocyte count and differential for the diagnosis of prosthetic knee infection.

Clin Infect Dis 2013;57:e22–e121. [29] Shannon SK, Mandrekar J, Gustafson DR, et al. Anaerobic thioglycolate broth culture for recovery of Propionibacterium acnes from shoulder tissue and fluid specimens. J Clin Microbiol 2013;51(2):731–732. [30] Colmenero JD, Morata P, Ruiz-Mesa JD, et al. Multiplex real-time polymerase chain reaction: a practical approach for rapid diagnosis of tuberculous and brucellar vertebral osteomyelitis. Spine 2010;35(24):E1392–E1396. [31] Parvizi J, Zmistowski B, Berbari EF, et al.

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